KMID : 0360220070480070911
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Journal of the Korean Ophthalmological Society 2007 Volume.48 No. 7 p.911 ~ p.918
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Long-term Results of Vision and Fundus Findings in X-Linked Juvenile Retinoschisis
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Lee Jong-Joo
Kim Jeong-Hun Choung Ho-Kyung Heo Jang-Won Kim Seong-Joon Yu Young-Suk
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Abstract
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Purpose: To evaluate long-term changes in visual acuity, fundus findings and complications in X-linked juvenile retinoschisis.
Methods: A retrospective chart review was conducted on 48 patients diagnosed with X-linked juvenile retinoschisis and followed for a minimum of 12 months.
Results: Forty-eight males (mean age 5.7 years) were followed for a mean of 6.3 years. The mean visual acuities were 0.14 at the initial and most recent examinations without significant change (p=0.67). Macular abnormalities were seen in all eyes. Macular lesions varied as follows: decreased foveal reflex (12.5%), typical foveal schisis (77.1%), atrophic change (5.2%), and macula-involving peripheral schisis (5.2%). When patients had different macular findings, the mean visual acuities were significantly different among groups (p¡Â0.005), except those between the atrophic change group and the macula-involving peripheral schisis group. Peripheral schisis was detected in 66% of patients. The fundus findings were stationary during the follow-up period except in complicated cases with vitreous hemorrhage (15.6%).
Conclusions: X-linked juvenile retinoschisis causes bilateral visual acuity loss, affecting maculae. In uncomplicated cases, changes in visual acuity and fundus findings were not significant during the follow-up period.
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KEYWORD
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Fundus findings, Visual acuity, X-Linked juvenile retinoschisis
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